How to to assess biologically relevant dermal exposures

The results of an attempt to develop a dermal sampler which will mimic the
uptake of solvent through the skin, has been produced as a research report by
the British Health and Safety Executive (HSE).

Occupational dermal exposure to hazardous substances is known to cause a
variety of diseases, including skin cancer and dermatitis. The prevalence of
occupational skin diseases is not known exactly, but there are probably many
workers affected. In addition, many chemicals such as pesticides and some
solvents may pass into the body through unbroken skin. The diseases caused by
dermal exposure, either alone or along with inhalation exposure, have important
social and economic consequences. However, there is little standardisation of
techniques for sampling skin exposure.

New studies show that it is possible to produce a practical sampler, of simple
construction, which is sufficiently robust to be used in workplace situations.
IOM also observed a relationship between inhalation exposure and dermal
exposure to toluene, depending on which part of the body the sampler was

Further information

AplusA-online.de - Source: Health and Safety Executive (HSE)